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My youngest son's wife is a fibromyalgia patient and has used CBD products for pain control. My wife has also tried it with some succes. This leads me to wonder if anyone else has tried it or considered doing so?

Your Guide To CBD Legalization By State    from Forbes Health

What is the difference between hemp CBD and cannabis CBD?            from Medical News Today 

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I've been using CBD oil sublingually for 3 years now for pain associated with 2 torn discs (L4/5). Before I was taking advil daily. I also have nerve ablations yearly for the pain. Using CBD has dramatically improved my pain and activity level.

May not work for everyone but it does for me. Tried gummies I bought at Qsite then tried CBD balm but find the oil works best. But it does take a few weeks for it to become effective.

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I wish I could. I will be doing the shots and possibly nerve ablations.

I used both CBD only and hybrid 5mg THC 20 mg CBD gummies that helped a bunch in relaxing nerve spasms like a 500mg Naproxin and a couple of drinks once we were settled in for the night.

I don't drink alcohol and can't use NSAIDs and cannot use Cannabis in any form safely with the blood thinners I have to take for life.

Life is still good.

I hope everyone finds some relief that is in pain. Cannabis can help some.

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14 minutes ago, RV_ said:

I don't drink alcohol and can't use NSAIDs and cannot use Cannabis in any form safely with the blood thinners I have to take for life.

According to drugs.com, changes in blood pressure is one of the more common side effects from use of cannabis. According to the mayoclinic.org CBD has fewer side effects but still should be consdiered. The reaction with other medications leaves a lot to think about.

Quote

Though it's often well-tolerated, CBD can cause side effects, such as dry mouth, diarrhea, reduced appetite, drowsiness and fatigue. CBD can also interact with other medications you're taking, such as blood thinners. Another cause for concern is the unreliability of the purity and dosage of CBD in products.

 

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Kirk, my Primary care doctor told me there is a risk of Eliquis levels rising when you take it with any MJ including just the CBD fraction. I just had my Cardiopulmonary specialist appointment last week and had researched it because I asked if they were safe to take together. He said the same and also that no testing has been done with Eliquis but it severely impacted blood levels of Coumadin which is the only blood thinner tested with CBD. Below is a quote from a pro CBD publication that mirrors what they told me.

I choose not to take the risk. I had my Coumadin levels skyrocket to an INR of 7.2 back in 2007 and was bruised head to toe. And I did not do any Cannabis products from 1971 -2019 when we moved here.

Excerpt:

"CBD and Eliquis

Taking CBD and Eliquis together may increase the blood levels of Eliquis, but we do not know this for sure. There are no studies that have tested drug interactions in people who are taking both at the same time. However, indirect research shows there may be an interaction. The body breaks down Eliquis mostly by using the enzymes CYP3A4 and P-GP. Studies have shown that CBD can inhibit both CYP3A4 and P-GP in humans. Since these are the enzymes that remove Eliquis from the body, taking CBD at the time may increase the levels of Eliquis in the blood.

A drug interaction that increases Eliquis levels can be dangerous. Increased levels of Eliquis can cause uncontrolled bleeding including bleeding in the brain, spine, eye, joints, abdomen or inside the pericardium — the sac that surrounds the heart. Unlike other anticoagulants, there is no easy way to reverse high levels of Eliquis. Andexanet Alfa can reverse Eliquis overdose, but it is only used in hospitals and is very expensive.

Do not, under any circumstances, start to take CBD if you are on a regimen of Eliquis without the knowledge and consent of your doctor. The risk is too great.

Why is Taking Eliquis and CBD Together a Risk?

Eliquis and CBDAdding CBD along with Eliquis can be risky because of interactions between CBD and liver enzymes. These enzymes are what metabolizes Eliquis and many other prescription medications. Let’s explore how Eliquis is metabolized and how CBD can play a role.

What is the First Pass Effect?

When you take Eliquis by mouth, it first enters the stomach before making its way to the body’s circulation. However, before entering the bloodstream it passes through the liver via the hepatic portal vein. Enzymes in the liver begin to break down the Eliquis, which is the body’s natural defense against toxins.

While passing through the liver, Eliquis is broken down into inactive metabolites. Usually, only a small fraction of what is swallowed actually makes it into your bloodstream. This process is called the First Pass Effect. When taken by mouth, about 50% of the dose ends up in the bloodstream.

The primary enzymes responsible for breaking down Eliquis and other medications that have entered the liver are cytochromes P450 (CYP). They are present in many different kinds of organisms and over 50,000 of them have been identified. Different medications are broken down by different CYPs inside the liver. More than 60% of medications are metabolized by P450 enzymes. Eliquis is primarily broken down by CYP3A4 and P-GP."

Source: https://cbdeducationonline.com/cbd-and-eliquis/

 

Edited by RV_
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10 hours ago, RV_ said:

I choose not to take the risk.

Reading that, along with some investigating of blood thinners and other heart medicines, I think I'd go that same way. Between your AF medic experience and your recent medications, you are far better informed on the subject than I. I happen to be one of those fortunate enough to have come from a long line of ancesters who had none of those medical issues and long lived parents. The only prescription meds that I take are on for prostate and a half does of Simvastatin. Pam does take a bunch of meds for a variety of issues so CBD conflicts with her medications are something that she has discussed with her primary care doctor and will be doing so later today with her pain management doctor later today. I suppose it is because I have had so little in my medical history, but I've never been much for digging into such subjects. 

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I seem to be one who has the reverse issue of clotting. I have only had surgery 2 times in my life, the first an appendix at 19 and the second back in Feb. for prostate. I had been taking an 81 mg asprin a day since it was suggested by my previous doctor more than 20 years ago. The urologist who did my surgery told me to stop taking it as it seems that I blead more than expected. 

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17 hours ago, bigjim said:

holy Crap

That was on the old rat poison in 2007 post my second knee surgery. They drew blood every Thursday, sent it out, and reported it back on Friday. The PA dropped my blood so I came in on Friday to draw it a second time. Over that weekend it was crazy bruising so I stopped taking it Friday night and both the Doc and his PA called me(Never called before either of them instead their nurse called for everything. They were freaked out thinking I was dead/stroked etc. They were shocked I felt OK and had me come in a couple of days later and wwanted me to continue. It was one month post second knee surgery and I had no DVT it was prophylaxis because I had one after my first knee surgery in 2003 - to keep another from happening. I stopped taking the Coumadin/warfarin after six months then. Eliquis is much more forgiving and no weekly blood draws, fewer drug interactions, and fewer dietary restrictions than that old rat poison.

But as I said, like my recent what the Pulmonologist called massive PEs and Calf DVT last September 30th, I dodged several big bullets that are hard to explain how with no damage. Yet have my two younger brothers die, one my only full brother of a massive MI in 2010 at 56 and the other a half brother last year who had a massive stroke and his wife pulled the plug after negative EEGs.  That prompted me to quit smoking and drinking alcohol in 2010 to maximize the years left. I can't believe I am 70 and relatively healthy! Here's to 20 more at least for both of us. 🖖My aunt just died at 93 and taught piano up to a month before she passed. No telling the why or when for each of us on Starship Earth.

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2 hours ago, RV_ said:

That prompted me to quit smoking and drinking alcohol in 2010 to maximize the years left. I can't believe I am 70 and relatively healthy! Here's to 20 more at least for both of us.

Congratulations on quitting smoking. You must have smoked for a long time was we quite back 30+ years ago after having smoked for 27 years and it was not a fun experience. I had cut back on the alcohol previous to that but still do drink a beer a couple of times a week and sometimes a little burbon with my eldest son.

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On 8/24/2022 at 7:07 PM, slackercruster said:

Does it dope you up? If no high, then I'd try. 

CBD is not hallucinogenic at all. The thing in marijuana or cannibus that makes one high is THC and the CBD products sold publicly have less than 0.3% but is there in trace amounts. It is not possible to get high from CBD products.

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2 hours ago, bigjim said:

So are the things called gummies  CBD or do they have THC in any significant amount?

No. As I stated before, they are limited by the FDA to have no greater than 0.3% THC in any publicly sold CBD product. If you investigate you will discover that nearly all CBD sold today comes from varieties of hemp that contian almost no THC because those varieties do contain more CBD. The varieties knows as cannabis or marijuana have far more THC and very little CBD.

How is cannabidiol different from marijuana, cannabis and hemp?

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Jim they sell them with no CBD THC only, which gets you high. They sell them with no THC CBD only that won't get you high. They sell them with both in varying amounts. 1:1 is the same mg of each. 10mg of THC is a standard dose to get high. Gummies are edibles that are the same as gummy bear candy but with THC and/or CBD in them.
 

It is a big learning curve to learn what works for you, and really no help from the store sales folks. It won't hurt you unless you're stupid enough to drive on it. So I experimented. The only advice I got was from online and I knew that 1:1 without giant doses worked better for pain and stress relief. In other words a little buzz helped the pain relief as much as the CBD. 

But YMMV.

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Posted (edited)

\

17 hours ago, bigjim said:

Just wanted to be really clear.

What they sell depends on who and where they are. CBD is available in oil, consumables (gummies are common), pills or tablets, and topicals (creams, salves, etc.) from places like Amazon and vendors at most large events. While the products generally have less than 0.3% THC, since they aren't FDA regulated you do need to take precautions and read labels, just as should be done for any over counter medications and supplements. Unless you are shopping in one of the states where cannabis has been legalized, you aren't likely to find it or THC available for sale and Amazon only sells CBD products. Speaking only for myself, I would only consider products that someone I knew and trusted would recommend. I have not personally used any type of CBD or cannabis. My wife has used a CBD cream for sciatica pain with some success and she tried gummies for back pain with very little improvement. She also tried some pills that were CBD & caffine that were less effective than Tylonal. We both did a lot of reading first and to date I have not had any reason to try them. When compared to over counter drugs, CBD products are quite expensive. There are many reliable sources for information on these products.

Medical News Today: Types of CBD: What to know

Mayo Clinic: What are the benefits of CBD — and is it safe to use?

Health Line: CBD Shopping Guide: Which Type of CBD Should You Buy?

The product that Pam has found to be helpful and will buy again is Spartakush Body Butter.

Edited by Kirk W
correct typo
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Kirk, Jim asked specifically about gummies. And wanted to be clear that CBD did not make one high.

On 8/27/2022 at 7:45 AM, bigjim said:

So are the things called gummies  CBD or do they have THC in any significant amount?

Anyone can go online and get confused so let me repeat what I wrote above: "The only advice I got was from online and I knew that 1:1 without giant doses worked better for pain and stress relief. In other words a little buzz helped the pain relief as much as the CBD. "

13 hours ago, RV_ said:

Jim they sell them with no CBD THC only, which gets you high. They sell them with no THC CBD only that won't get you high. They sell them with both in varying amounts. 1:1 is the same mg of each. 10mg of THC is a standard dose to get high. Gummies are edibles that are the same as gummy bear candy but with THC and/or CBD in them.
 

It is a big learning curve to learn what works for you, and really no help from the store sales folks. It won't hurt you unless you're stupid enough to drive on it. So I experimented. The only advice I got was from online and I knew that 1:1 without giant doses worked better for pain and stress relief. In other words a little buzz helped the pain relief as much as the CBD. 

But YMMV.

Kirk have you used any of these? So far you are talking about your wife and ordering online. You did not mention shatter or wax forms of MJ nor a dozen others, We have teas, sodas, plastic inhalers vape oils, cookies, cakes, all kinds of ways I haven't tried yet and won't because I cannot any more. But that wasn't what Jim asked about.

Have you been in a dispensary or recreational store and talked with the sales folks? If so which state? Here they will not allow a spouse without a state card to enter with the card holder.

Here you don't need back door or alleyway advice or word of mouth, it is like pharmacy goods in dispensaries, and in recreational stores like OTC drugs at WalMart. You go in and shop and buy whatever you like. You cannot even enter a dispensary without your state issued license/authorization here, not even to see the prices. I do not know about other states. But I got 30 gummies with 10mg THC 10mg CBD in each for $19 at the dispensary. Think of 30 sets of four 12 oz beers for a cost comparison. The effect lasts several hours so one a day was enough for me in the evenings once in for the night.

I highlighted and underlined what is important. Everyone told me that CBD works best with a little THC. Everyone's metabolism is different and each of us ina legal state has to experiment first hand to be able to pass on info.

I have never experienced any buzz from CBD only oils pills gummies etc.

CBD alone did nothing for my lumbar issues but some THC made it much more effective. I also did the oils under my tongue for my first experiments here. I  not like being drunk or stoned and certainly not hallucinating. So I never took giant doses like some folks I met in the stores do. The chocolates were ten squares and cost

MJ will show up in drug tests if arrested so I never drove even on only CBD. I won't smoke as my lungs took enough abuse from smoking. My docs all said not to take MJ with blood thinners including Eliquis which I take. So I have no dog in this fight pro or con just first hand experience. If anyone has any specific questions I will try to answer them. I have no cravings for MJ nor have any physical issues when I stopped from the Pulmonary embolism. So no pro MJ agenda nor anti-MJ hearsay to promote. To be honest I miss my Naproxin (Alleve) NSAID as it did more than CBD as far as pain relief and drinking some beers after taking Naproxin relaxed me even more with the pain relief so the idea of a little THC with CBD made sense to me. CBD alone never really worked alone for me.

Here is a store website which will totally confuse a newbie as they did me at first. Just click around on the different ways and methods to take MJ CBD?THC.

https://www.tgscolorado.com/shop

If you go to the website verify you are of age select any store and then scroll down to where you see this menu and click on each one to see each kind and then use checkmarkboxes to see more and scrolll down all the way on each page after checking candies etc:

Shop

Safe travels!

Edited by RV_
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6 hours ago, Kirk W said:

What they sell depends on who and where they are. CBD is available in oil, consumables (gummies are common), pills or tablets, and topicals (creams, salves, etc.) from places like Amazon and vendors at most large events. While the products generally have less than 0.3% THC, since they aren't FDA regulated you do need to take precautions and read labels, just as should be done for any over counter medications and supplements. Unless you are shopping in one of the states where cannabis has been legalized, you aren't likely to find it or THC available for sale and Amazon only sells CBD products. Speaking only for myself, I would only consider products that someone I knew and trusted would recommend. I have not personally used any type of CBD or cannabis. My wife has used a CBD cream for sciatica pain with some success and she tried gummies for back pain with very little improvement. She also tried some pills that were CBD & caffine that were less effective than Tylonal. We both did a lot of reading first and to date I have not had any reason to try them. When compared to over counter drugs, CBD products are quite expensive. There are many reliable sources for information on these products.

Medical News Today: Types of CBD: What to know

Mayo Clinic: What are the benefits of CBD — and is it safe to use?

Health Line: CBD Shopping Guide: Which Type of CBD Should You Buy?

The product that Pam has found to be helpful and will buy again is Spartakush Body Butter.

Did you order or go into a store where legal?

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