Jump to content
Sign in to follow this  
RV_

Axon Neuroscience announces positive results from Phase II trial for a cure to Alzheimer’s Disease

Recommended Posts

Today, Axon Neuroscience has announced the results of the Phase II trial for AADvac1, its first-in-class vaccine aimed at slowing down the progression of Alzheimer’s Disease.

The Phase II ADAMANT trial was designed as a randomized, double-blinded, placebo-controlled trial in mild Alzheimer’s Disease. The primary objective was safety, with secondary objectives to evaluate immunogenicity, efficacy on clinical outcomes and key biomarkers.

Axon studied AADvac1 on 196 patients in eight European countries over 24 months, in order to prove the concept of disease modifying effect of the vaccine and to inform the design of future confirmatory studies.

Dr James Pickett, Head of Research at Alzheimer’s Society, said:

'We have seen the failure of many amyloid targeting drugs for Alzheimer’s over the past few years, so all eyes are on tau to see if targeting it could help stave off the condition.

More here: https://www.alzheimers.org.uk/news/2019-09-09/axon-neuroscience-announces-positive-results-phase-ii-trial-cure-alzheimers-disease

 

Share this post


Link to post
Share on other sites

I cared for my mother as she went through dementia. Never did have full blown Alzheimer's but still bad and eventually destroyed her memory. She lived with it for 7 years after diagnosis, 5 of those in long term care. We suspect she had early stage for several years before diagnosis. 

Quote

'The results suggest the mechanics of the drug are working, but we shouldn’t get too excited as we’ve seen this before in early trials of drugs, that have then turned out to fail.  We now know that the drug is safe, can activate the immune system and may have positive effects in this small group of people. What we need now is large-scale trials which will have the power to find out whether this drug could be capable of slowing down Alzheimer’s. Research will beat dementia, but we need funding to make it happen.'

 

Share this post


Link to post
Share on other sites

Join the conversation

You can post now and register later. If you have an account, sign in now to post with your account.

Guest
Reply to this topic...

×   Pasted as rich text.   Paste as plain text instead

  Only 75 emoji are allowed.

×   Your link has been automatically embedded.   Display as a link instead

×   Your previous content has been restored.   Clear editor

×   You cannot paste images directly. Upload or insert images from URL.

Loading...
Sign in to follow this  

RVers Online University

campgroundviews.com

Our program provides accurate individual wheel weights for your RV, toad, and tow vehicle, and will help you trim the pounds if you need to.

DFW RV Roof

RVAir The cleanest air in RVing!

Rv Share

Dish For My RV.

Find out more or sign up for Escapees RV'ers Bootcamp.

Advertise your product or service here.

The Rvers- Now Streaming

AGS Now Hiring

RV Pet Safety

RVTravel.com Logo



×
×
  • Create New...