Some good info above. Our Volvo was our daily driver for 3ish years. We were on the road full time and during the summers have moved about the same as you describe, 4 hour travel, every few days to a week.
Grocery store and hardware store runs got to be routine, hand the stuff up, then hand it back down.
We were at a slight disadvantage in places like Yellowstone, some roads prohibit RV’s and buses for good reason. Parking in downtown San Antonio to visit the Alamo was a problem. We ended up taking the bus. Just rare examples.
if I had it to do over again, I might have our Volvo 730 singled short like Av8r. Like you, I probably would choose a short sleeper since we never use it. The sleeper is probably a requirement in any state that allows converting to RV.
The air-up and warm-up never bothered me much.
It has taken me a long time to get used to the hard banging on potholes. It throws the drinks out of the cup holder and my wife can’t sleep on the mattress.
I agree with Rickeieio that climbing up and down has disadvantages. I’ve heard that is where most truckers get injured, but that has only influenced me enough to be more conscious while climbing. We have stayed at a couple of parks where the time it takes to punch in the gate code is too long to drive through it. I have to have another person punch it in. Neither of those reasons would be a deciding factor for me. Just inconvenient occasionally.
I haven’t had a big diesel pickup to compare. That’s what I was looking for when I found these sites for HDTs. I will say I absolutely love my HDT when pulling the RV. Only the strongest crosswinds affect it at all. If the trailer brakes have a problem it’s not a big deal to drive until you can get them fixed. Not recommended of course. I didn’t know I had gotten air in the brake lines and drove for awhile before I noticed. These things happen.
Blessings and good luck. Kevin.